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AQ Column

HPLC
UPLC


InertSustain AQ-C18


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InertSustain AQ-C18 LC Columns

AQ column Maximizing retention for highly polar compounds in reversed phase methods with highly aqueous mobile phases

InertSustain AQ-C18 columns are designed to achieve strong retention for highly polar compounds, which is the most challenging goals in developing reversed phase methods. The optimization of bonding of the C18 groups at equal distance to the silica gel enable InertSustain AQ-C18 to offer significant retention for highly polar compounds even under water rich mobile phases.

Recommended for applications where 100% aqueous mobile phases are required. Ideal for fast gradients due to rapid re-equilibration properties.

Highly Polar Compound Retention with 100% Aqueous Mobile Phases
It is indeed difficult to retain highly polar samples by reversed phase mode as the polar samples tend to elute near the t0 with water rich mobile phases. On the other hand, polar embedded C18 columns or C18 columns with hydrophilic endcapping are available in the market for retaining highly polar compounds. However, they often show tailing or poor peak shapes due to the secondary interaction from their embedded functional groups. InertSustain AQ-C18 not only provide strong retention for highly polar compounds, but also delivery symmetric peak shapes for virtually any type of analytes.

Highly Polar Compound Retention with 100% Aqueous Mobile Phases on AQ column

The AQ column is avaiable in Metal, PEEK, Preparative, Capillary and Steel-Coated PEEK. The InertSustain AQ HPLC Column is both for UPLC and HPLC.

AQ HPLC Column

    AQ-C18 Column information shop your AQ Column  
Particle
Size
I.D. (mm) Particle
Shape
Surface
Area
Pore
Size
Pore
Volume
Silica
Purity
Bonded
Phase
End-
Capping
Carbon
Load
pH
Range
USP
Code
1.9, 3, 5 µm 1.0, 1.5, 2.1,
3.0, 4.0, 4.6, prep
Spherical 350 m2/g 100Å 0.85 mL/g 99.999% Octadecyl
Groups
Complete 13% 1 - 10 L1

Related Applications

Analysis of Fatty acids by LC/MS/MS
Analysis of Pyridoxal Phosphate Hydrate (JP Pharmacopoeia, (4) Related subatances)
Analysis of Polar Peptides
Analysis of Tranexamic acid (JP Pharmacopoeia, Tranexamic acid Tablets)
Analysis of Tranexamic acid (JP Pharmacopoeia)
Analysis of Nucleotide
Analysis of Aflatoxin M1
Analysis of Digested BSA
Analysis of Digested Myoglobin
Analysis of Povidone (JP Pharmacopoeia 17th edition, (6) 2-Pyrrolidone)
Analysis of Povidone (JP Pharmacopoeia 17th edition, (4) 1-Vinyl-2-pyrrolidone)
Analysis of Zonisamide 4-Aminoacetophenone, Zonisamide
Analysis of Zonisamide Zonisamide
Analysis of Vitamin K
Analysis of Hippuric acid
Analysis of Preservatives and Sweetener
Analysis of Preservatives and Sweetener
Analysis of 9 Drugs
Analysis of Methacrylic acid
Analysis of 12 Drugs
Analysis of Angiotensin II receptor blockers
Analysis of ATP related compounds
Analysis of Hippuric Acids
Analysis of 13 kinds of Aldehydes (Directed by Pre-Column Method with DNPH)
Analysis of Nucleoside and Nucleic acid base
Analysis of Water-soluble Vitamins
Analysis of Organic acid
Analysis of ß-blocker
Analysis of Furfral and 5-Hydroxymethylfurfral